NANO-BIO-MATERIALS

The group Nanobiomaterials develops drug release systems and tissue engineering scaffolds for various applications. Nanoporous materials often play a major role as reservoirs for drug release systems. Within our work, we apply nanoporous silica and metals as well as organic-inorganic hybrid materials, for example as coatings or nanoparticles. As a special material, superparamagnetic core-shell nanoparticles are investigated as well.

Research

GROUP LEADER
Prof. Dr.
Peter Behrens
Working Group Leader
Institute for Inorganic Chemistry
GROUP LEADER
Dr.
Nina Ehlert
Post Doc, Group Head NIFE
Institute for Inorganic Chemistry
M. Sc.
Mosaieb Habib
PhD student
M. Sc.
Valentin Hagemann
PhD student
M. Sc.
Timo Herrmann
PhD student
M. Sc.
Florian Klodwig
PhD student
M. Sc.
Monika Seegers
PhD student
M. Sc.
Luisa Vanessa Steingrube
PhD student
M. Sc.
Saskia Zailskas
Post-doc

Publications:

I. Wille, J. Harre, S. Oehmichen, M. Lindemann, H. Menzel, N. Ehlert, T. Lenarz, A. Warnecke, P. Behrens
Development of Neuronal Guidance Fibers for Stimulating Electrodes: Basic Construction and Delivery of a Growth Factor
Frontiers Bioeng. Biotechnol. 10 (2022) 776890

S. Zippusch, K. F. W. Besecke, F. Helms, M. Klingenberg, A. Lyons, P. Behrens, A. Haverich, M. Wilhelmi, N. Ehlert, U. Böer
Chemically induced hypoxia by dimethyloxalylglycine (DMOG)-loaded nanoporous silica nanoparticles supports endothelial tube
formation by sustained VEGF release from adipose tissue-derived stem cells
Rain. Biomater. 8 (2021) rbab039

M. Jahns, D. P. Warwas, M. R. Krey, K. Nolte, S. König, M. Fröba, P. Behrens.
Nanoporous hybrid core-shell nanoparticles for sequential release.
J. Mater. Chem. B 8 (2020) 776-786

S. Ullah, K. Seidel, S. Türkkan, D.P. Warwas, T. Dubich, M. Rohde, H. Hauser, P. Behrens, A. Kirschning, M. Köster, D. Wirth
Macrophage entrapped silica coated superparamagnetic iron oxide particles for controlled drug release in a 3D cancer model.
J. Control Release 294 (2018) 327-336

N. Schmidt, J. Schulze, D.P. Warwas, N. Ehlert, T. Lenarz, A. Warnecke, P. Behrens. Long-term delivery of brain-derived neurotrophic factor (BDNF) from nanoporous silica nanoparticles improves the survival of spiral ganglion neurons in vitro.
PLoS ONE 13 (2018) e0194778

 

D. de Cassan, S. Sydow, N. Schmidt, P. Behrens, Y. Roger, A. Hoffmann, A.L. Hoheisel, B. Glasmacher, R. Hänsch, H. Menzel
Attachment of nanoparticulate drug-release systems on poly(ε-caprolactone) nanofibers via a graftpolymer as interlayer.
Colloids Surf. B: Biointerfaces 163 (2018) 309-320

H. Fullriede, P. Abendroth, N. Ehlert, K. Doll, J. Schäske, A. Winkel, S.N. Stumpp, M. Stiesch, P. Behrens
pH-responsive release of chlorhexidine from modified nanoporous silica nanoparticles for dental applications.
BioNanoMaterials 17 (2016) 59-72

read more
Keywords
Nanobiomaterials, nanoporous biomaterials, nanoporous nanoparticles, superparamagnetic nanoparticles, nanoporous implant coatings, polymer-nanoparticle composites, organic-inorganic hybrid materials, controlled drug release, growth factors, tissue engineering
Contact

Prof. Dr. Peter Behrens

+49 (0) 511 762 3660 / 3697

peter.behrens(at)acb.uni-hannover.de

Leibniz University Hanover
Institute for Inorganic Chemistry
Callin Street 9
30167 Hanover

 

Contact in NIFE

Dr. Nina Ehlert

+49 (0)511 532 1321 / 1317

nina.ehlert(at)acb.uni-hannover.de

NIFE
Stadtfelddamm 34
30625 Hanover

 

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