The group Nanobiomaterials develops drug release systems and tissue engineering scaffolds for various applications. Nanoporous materials often play a major role as reservoirs for drug release systems. Within our work, we apply nanoporous silica and metals as well as organic-inorganic hybrid materials, for example as coatings or nanoparticles. As a special material, superparamagnetic core-shell nanoparticles are investigated as well.
I. Wille, J. Harre, S. Oehmichen, M. Lindemann, H. Menzel, N. Ehlert, T. Lenarz, A. Warnecke, P. Behrens
Development of Neuronal Guidance Fibers for Stimulating Electrodes: Basic Construction and Delivery of a Growth Factor
Frontiers Bioeng. Biotechnol. 10 (2022) 776890
S. Zippusch, K. F. W. Besecke, F. Helms, M. Klingenberg, A. Lyons, P. Behrens, A. Haverich, M. Wilhelmi, N. Ehlert, U. Böer
Chemically induced hypoxia by dimethyloxalylglycine (DMOG)-loaded nanoporous silica nanoparticles supports endothelial tube
formation by sustained VEGF release from adipose tissue-derived stem cells
Rain. Biomater. 8 (2021) rbab039
M. Jahns, D. P. Warwas, M. R. Krey, K. Nolte, S. König, M. Fröba, P. Behrens.
Nanoporous hybrid core-shell nanoparticles for sequential release.
J. Mater. Chem. B 8 (2020) 776-786
S. Ullah, K. Seidel, S. Türkkan, D.P. Warwas, T. Dubich, M. Rohde, H. Hauser, P. Behrens, A. Kirschning, M. Köster, D. Wirth
Macrophage entrapped silica coated superparamagnetic iron oxide particles for controlled drug release in a 3D cancer model.
J. Control Release 294 (2018) 327-336
N. Schmidt, J. Schulze, D.P. Warwas, N. Ehlert, T. Lenarz, A. Warnecke, P. Behrens. Long-term delivery of brain-derived neurotrophic factor (BDNF) from nanoporous silica nanoparticles improves the survival of spiral ganglion neurons in vitro.
PLoS ONE 13 (2018) e0194778
D. de Cassan, S. Sydow, N. Schmidt, P. Behrens, Y. Roger, A. Hoffmann, A.L. Hoheisel, B. Glasmacher, R. Hänsch, H. Menzel
Attachment of nanoparticulate drug-release systems on poly(ε-caprolactone) nanofibers via a graftpolymer as interlayer.
Colloids Surf. B: Biointerfaces 163 (2018) 309-320
H. Fullriede, P. Abendroth, N. Ehlert, K. Doll, J. Schäske, A. Winkel, S.N. Stumpp, M. Stiesch, P. Behrens
pH-responsive release of chlorhexidine from modified nanoporous silica nanoparticles for dental applications.
BioNanoMaterials 17 (2016) 59-72
Prof. Dr. Peter Behrens
+49 (0) 511 762 3660 / 3697
Leibniz University Hanover
Institute for Inorganic Chemistry
Callin Street 9
Contact in NIFE
Dr. Nina Ehlert
+49 (0)511 532 1321 / 1317